Research On Tocotrienols

Immune Booster

Year Study
2010 Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers
2013 Supplementation with tocotrienol-rich fraction alters the plasma levels of Apolipoprotein A-I precursor, Apolipoprotein E precursor and C-reactive protein precursor from young and old individuals


Year Study
2018 Comparing Palm Oil, TRF and a-Tocopherol Supplementation on the Antioxidant Levels of Older Adults

Cardiovascular Health

Year Study
1991 Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols
1991 Effect of a palm oil- vitamin E concentrate on the serum and lipoprotein lipids in humans
1995 Response of hypercholesterolemic subjects to administration of tocotrienols
1997 Novel tocotrienols of rice bran modulate CVD risk of parameters of hypercholesterolemic humans
2000 Dose-dependent suppression of serum cholesterol by tocotrienol-rich fraction (TRF25) of rice bran in hypercholesterolemic humans
2002 Tocotrienol rich fraction supplement reduces oxidative stress in non familial hypercholesterolaemia: beyond the lipid lowering capability
2012 Differential serum responses of tocopherols and tocotrienols during vitamin supplementation in hypercholesterolaemic individuals without change in coronary risk factors
2011 Effect of Mixed-Tocotrienols in Hypercholesterolemic Subjects
2011 TRF supplementation improved lipid profile and oxidative status in healthy older adults : A randomized controlled study
2018 Tocotrienol rich fraction supplement reduces oxidative stress in non familial hypercholesterolaemia : beyond the lipid lowering capability


Year Study
2009 Tocotrienols Suppress Proinflammatory Markers and Cyclooxygenase-2 Expression in RAW264.7 Macrophages

Skin and Hair

Year Study
2009 Effects of oral gold Tri.E supplemetation for SD Research by Julianto
2010 Effects of Tocotrienol Supplementation on Hair Growth in Human Volunteers

Liver Protection

Year Study
2012 Oral Tocotrienols Are Transported to Human Tissues and Delay the Progression of the Model for End-Stage Liver Disease Score in Patients
2013 NFALD
2013 Tocotrienols for normalisation of hepatic echogenic response in nonalcoholic fatty liver : A randomised placebo-controlled clinical trial
2015 Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury
2018 The Effect of Tocotrienol-Rich Fraction on the Expression of Glutathione S-Transferase Isoenzymes in Mice Liver
2018 Effects of d-tocotrienol supplementation on liver enzymes and hepatic steatosis in patients with NAFLD
2018 The Effect of vitamin E on the liver stiffness measurement measured by fibroscan among NAFLD patients

Brain Health

Year Study
2014 Clinical Investigation of the Protective Effects of Palm Vitamin E Tocotrienols on Brain White Matter
2019 Vitamin E and Alzheimer’s disease : the mediating role of cellular aging

Anti Aging

Year Study
2008 Reduction of DNA damage in older healthy adults by Tri E®Tocotrienol supplementation
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